ActiveDriverDB是一个在线数据库，旨在可视化和探索影响人类蛋白质/基因（hg19/GRCh37）翻译后修饰（PTM）位点的突变。该数据库包括蛋白质、上游酶（如激酶）和靶向这些酶的药物的特定位点相互作用网络。

ActiveDriverDB是一个人类蛋白基因组数据库。该数据库使用有关蛋白质翻译后修饰（PTMs）的信息来注释和解释遗传变异、疾病基因和癌症驱动基因。ActiveDriverDB中的所有数据集都是从公共资源中收集的，并基于实验数据。可以从一些示例查询（MAPT中的痴呆突变、CFTR中的囊性纤维化突变、CTNNB1磷酸化蛋白中的癌症突变）开始探索数据集，交互式浏览、批量下载或使用应用程序接口（API）检索。用户还可以上传自己的自定义数据集，并在服务器上存储有限的时间。

ActiveDriverDB is an online database developed to visualize and explore mutations affecting post-translational modification (PTM) sites in human proteins/genes (hg19/GRCh37).The database includes site-specific interaction networks of proteins, upstream enzymes such as kinases, and drugs targeting these enzymes.

ActiveDriverDB is a human proteo-genomics database. The database uses information about post-translational modifications (PTMs) in proteins to annotate and interpret genetic variation, disease genes, and cancer driver genes. All datasets in ActiveDriverDB is collected from public resources and based on experimental data. The datasets can be explored starting from some example queries (dementia mutations in MAPT, cystic fibrosis mutations in CFTR, cancer mutations in CTNNB1 phosphodegron), browsed interactively, downloaded in bulk or retrieved using an application program interface (API). Users can also upload their own custom datasets and store on the server for a limited time.